Found 8 matching trials
A 2-part Study to Investigate the Effect of Macitentan in Healthy Male Participants
PHASE1The purpose of this study is to evaluate the effect of macitentan at steady...
Location
Clinical Pharmacology Unit
Riociguat rEplacing PDE-5i Therapy evaLuated Against Continued PDE-5i thErapy
PHASE4To demonstrate the effectiveness of riociguat as replacement of phosphodies...
Location
Multiple Locations
Riociguat Clinical Effects Studied in Patients With Insufficient Treatment Response to Phosphodiesterase-5 Inhibitor
PHASE3BAY63-2521 Riociguat leads to the relaxation of smooth muscle cells in pulm...
Location
Multiple Locations
A Study to Evaluate Efficacy and Safety of Oral BAY63-2521 in Patients With CTEPH.
PHASE3The aim of the study is to assess the efficacy and safety of different dose...
Location
Multiple Locations
Evaluation of the Pharmacodynamic Effect of the Combination of Sildenafil and Riociguat on Blood Pressure and Other Safety Parameters.
PHASE2Pulmonary Arterial Hypertension (PAH) is a severe progressive disease with ...
Location
Multiple Locations
Bioequivalence Study of Riociguat 2.5 mg Film Coated Tablets and Adempas (Riociguat) 2.5 mg Film Coated Tablets
PHASE1Single dose oral bioequivalence study of Riociguat 2.5 mg film coated table...
Location
Cliantha Research Limited
A Study to Evaluate Efficacy and Safety of Oral BAY63-2521 in Patients With Pulmonary Arterial Hypertension (PAH)
PHASE3The aim of the study is to assess the efficacy and safety of different dose...
Location
Multiple Locations
Clinical Study to Investigate Effect of Macitentan on Riociguat Pharmacokinetics
PHASE1Both macitentan and riociguat are indicated in the treatment of pulmonary a...
Location
CRS Clinical Research Services Mannheim